9- (2-Hydroxy) etoksimetilguanin, or 2-amino-1, 9-dihydro-9- (2-hydroxy) ethoxymethyl-6H-purin-6-one.
Synonyms: Viroleks, Zovirax, Asusloguanosine, Acyclovir, Cycloviran, Milavir, Virolex.
Protivovirucny drug, especially effective against viruses of herpes simplex and herpes zoster (zoster).
Acyclovir is an analogue of purine nucleoside dezoksiguanidina, normal DNA component.
The similarity of structures and acyclovir acyclovir dezoksiguanidina allows to interact with the viral enzymes, which leads to an interruption of viral replication. After introduction of acyclovir into an affected cell herpes thymidine kinase under the influence of released virus, acyclovir is converted into acyclovir monophosphate which enzymes of the host cell transformed in acyclovir diphosphate and then to the active acyclovir triphosphate form, which blocks the implementation of the viral DNA. The drug acts selectively on viral DNA synthesis. DNA replication hoeyaina cells (human cells) acyclovir triphosphate almost no effect.
Acyclovir herpes prevents new elements disease, reduces the likelihood of cutaneous dissemination and visceral complications accelerates education crusts, reduces pain in the acute phase of herpes zoster.
Acyclovir also has immunostimulatory effects.