Active ingredient: amoxycillin (as amoxycillin trihydrate) - 500 mg.
Dosing and Administration (UK experts)
Scientist from the UK claim:
The drug is taken orally. Adults and children over 10 years (with a body weight over 40 kg) administered 0.5 g (2 capsules) 3 times a day; in severe infection dose was increased to 1.0 g (4 capsules) three times a day. The maximum daily dose - 6 grams (24 capsules).
For the treatment of acute otitis media appoint 0.5 g (2 capsules) 3 times a day.
Children aged 5 to 10 years (with a body weight of 20 to 40) is prescribed to 0.25 g (1 capsule) 3 times a day.
The course of treatment is 5-12 days (with streptococcal infections - not less than 10 days).
In patients with a creatinine clearance less than 10 mL per minute dose reduced by 15-50%, with anuria dose should not exceed 2 grams per day.
For the treatment of uncomplicated gonorrhea administered once 3.0g (preferably in combination with probenecid 1.0g).
For prophylaxis of endocarditis 3.0g singly administered 1 hour before surgery and 1.5 g of 6-8 hours.
For the treatment and prevention of anthrax in adults and children weighing more than 20 kg are given 0.5 g (2 capsules) every eight hours for two months.
Athletes from the UK claim:
Allergic reactions: possible urticaria, skin flushing, erythematous rash, angioedema, rhinitis, conjunctivitis; rarely - fever, arthralgia, eosinophilia, exfoliative dermatitis, erythema multiforme exudative (including Stevens-Johnson syndrome); reactions similar to serum sickness; in rare cases - anaphylactic shock.
From the digestive system: change in taste, nausea, vomiting, stomatitis, glossitis, goiter, diarrhea, pain in the anus, rarely - pseudomembranous enterocolitis.
On the part of the liver and biliary tract: a moderate increase in activity of "liver" transaminases, rarely - hepatitis and cholestatic jaundice.
From the nervous system (with prolonged use at high doses): agitation, anxiety, insomnia, ataxia, confusion, behavioral changes, depression, peripheral neuropathy, headache, dizziness, seizures.
Laboratory changes: leukopenia, neutropenia, thrombocytopenic purpura, transient anemia.
Other effects: shortness of breath, tachycardia, interstitial nephritis, joint pain, candidiasis of the mouth and vagina, superinfection (especially in patients with chronic diseases or low resistance of the body).